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At one point, Trulicity was the most prescribed GLP-1 receptor agonist (RA) in the United States

Transporter assays for SGLT1 (Sodium-GLUcose Transporter 1) and GLUT2 (Glucose Transporter 2) are also available

Can Service Members use investigational GLP-1 drugs

Reducing inflammation directly benefits mood and brain function

Retatrutide TRIUMPH-1 (2023) and TRIUMPH-2 (2024) TRIUMPH-1 (Jastreboff et al., NEJM 2023): 338 non-diabetic adults with obesity, 48 weeks at escalating doses: 12 mg dose: 24.2% weight loss 8 mg dose: 22.8% 4 mg dose: 17.5% Placebo: 2.1% TRIUMPH-2 (Rosenstock et al., Lancet 2024) confirmed effects in T2D patients with concurrent NAFLD improvement (hepatic fat reduction 54% at 24 weeks, 12 mg dose)